ABSTRACT
No abstract available.
ABSTRACT
Sixty cutaneous tumors of different types were investigated by means of immunoperoxidase technique(avidin-biotm-peroxidase complex method) with the use of antikeratin antibody. The results were as follows: 1. Squamous cell carcinomas, keratoacanthomas, and Bowen's disease exhibited strong reactivity with antikeratin antibody. 2. In squamous cell carcinomas and keratoacanthomas, the most heaviest staining patterns were detected in areas of keratinization and horn pearl formation. 3. Basal cell carcinomas and seborrheic keratosis were moderately stained, whereas Paget'a disease and metastatic carcinoma(oat cell carcinoma) did not contain keratin. 4. In some cases of basal cell carcinomas, the tumor cells were partially positive. 5. Malignant melanomas, nevi, malignant.lymphomas, neural tumors, hemangiomas, and dermatofibromas were uniformly negative.
Subject(s)
Animals , Bowen's Disease , Carcinoma, Basal Cell , Carcinoma, Squamous Cell , Hemangioma , Histiocytoma, Benign Fibrous , Horns , Keratoacanthoma , Keratosis, Seborrheic , Melanoma , NevusABSTRACT
Partial unilateral lentiginosis(PUL) is a rare pigmentary disorder charaeterized by lentigines limited to one side of the body with or without neurologic abnormalities. We report two cases of PUL unassociated with any other defect, One patient was 20-year-old female who had lentigines confined to the right side of the face and the other was 19-year-old male who had lentigines confined to the left side of the neck and upper trunk and left upper extremity. Histologic examination of the pigmented lesion revealed findings consistent with lentigo simplex.
Subject(s)
Female , Humans , Male , Young Adult , Lentigo , Neck , Upper ExtremityABSTRACT
Sebaceous adenoma is a benign organoid tumor of proliferating, incornpletely differentiated sebaceous glands. We report a case of sebaceous adenoma in a 15-year-old male. He had a 1.7 x 2.2 cm sized, asymptomatic, srnooth, round, raised, firm, reddish tumor on the left quadrant of abdomen. Histopathologically, the tumor was composed of lobules of irregular size and shape, and sharply demarcated from the surrounding tissue, The most lobules showed undifferentiated germinative and mature sebaceous cells in about equal number. Sebaceous cells in lobules were stained for prekeratin by means of avidin-biotin-peroxidase complex method. Ten months after surgical excision there was no evidence of recurrence.
Subject(s)
Adolescent , Humans , Male , Abdomen , Adenoma , Organoids , Recurrence , Sebaceous GlandsABSTRACT
Sixty-one cases in which the diagnosis of epithelial cysts had been made studied. The data were collected from our own clinical records and a review of all histopathologic slides of epithelial aysts that had been filed at Departrnent of Dermatology, Chosun University Hospita.l during the past g years from July, 1979 to June, 1984. The results were as follows: 1) Among the 61 cases of epithelial cysts, 41 cases were epidermal cysts, 10 cases of milia, 7 cases of steatocystoma. multiplex, 2 cases of pilar cysts and 1 case of eruptive vellus hair cyst. 2) The average age of these patients was third decade. 3) The commonest site of epidermal cyst and milium was face. Two cases of pilar cyst occurred only on the scalp. Fteatocystoma multiplex was developed on the several sites, but not on the scalp and scrotum, 4) The average diameter was 6. 5 mm for epidermal cyst, p 6 mm for milium, 3 1 mm for steatocystoma multiplex and 17 mm for pilar cyst.
Subject(s)
Humans , Dermatology , Diagnosis , Epidermal Cyst , Hair , Scalp , Scrotum , Steatocystoma MultiplexABSTRACT
We herein present two cases of angioleiomyoma with unusual location and number of cutaneous lesion. One was 58-year-old male who has two small peasized nodules on the left palm and volar aspect of the left fifth finger. The other was 63-year-old male with three small pea-sized nodules on the left palm, volar aspect of the left middle finger and the right sole. We confirmed these as angioleiomyoma by clinical and histopathological findings.
Subject(s)
Humans , Male , Middle Aged , Angiomyoma , FingersABSTRACT
We report an atypieal case of xanthoma without evidence of underlying disease, A 50-year-old asymptomatic, yellowish, flat plaques on the upper eyelids, trunk and thighs, and huge, deep-seated tumors on anterior aspect of the neck, back and ankle areas of 3 years duration. Biopsies were performed at the lesions of the neck and hack. Two biopsy specimens showed the same findings of xanthoma, respectively. The appearance of refrigerated serum was clear. Paper electrophoresis didn't show elevation of any lipoprotein, suggesting normolipoproteinemia.
Subject(s)
Humans , Middle Aged , Ankle , Biopsy , Electrophoresis, Paper , Eyelids , Lipoproteins , Neck , Thigh , XanthomatosisABSTRACT
Subepidermal calcified nodules, consisting of solitary circumscribed deposits of insoluble calcium within the subepidermis, have generally been assumed to be idiopathic. As the disease is not associated with any systemic or cutaneous diseases, or any biochemical abnormalities, the pathogenesis is still unexplained, and it is thought to be a definite entity with only a characteristic histopathology. We report a 36-year-old female who has had subepidermal calcified nodules on both upper eyelids symmetrically for about 20 years. It is interesting that the lesions have xanthelasma-like appearance and are associated with syringomas. Excisional biopsy showed typical histopathologic and histochemical features of the sub epidermal calcified nodules.